In the last few decades, pyrazole chemistry has attracted chemists’ and biologists’ attention mainly due to the discovery of the interesting properties of a great number of pyrazole derivatives. The resulting proliferation of research literature reflects the enormous biological potential of pyrazole derivatives as antitumor, anti-inflammatory, anti-HIV and antimicrobial agents. This review focuses on research concerning the antimicrobial activity of pyrazole derivatives conducted from 2010-2018, and is intended to assist in the development of a new generation of antimicrobial drugs.

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吡唑类药物的抗菌潜力简述（2010-2018年）

在过去的几十年中，吡唑化学引起了化学家和生物学家的关注，这主要是由于发现了许多吡唑衍生物的有趣特性。研究文献的大量涌现反映出吡唑衍生物作为抗肿瘤，抗炎，抗HIV和抗微生物剂具有巨大的生物学潜力。这篇综述着重于2010年至2018年进行的有关吡唑衍生物的抗菌活性研究，旨在协助开发新一代抗菌药物。