Background: Many antibiotics were widely used as medication based on their distinctive features. Among them, sulphonamides were commonly and mainly used for bacterial treatment, however, the recalcitrant nature makes them difficult to dispose of. Hence, their interaction with the environment and analytic technique requires considerable attention globally.

Objective: Therefore, this review aimed to provide a detailed discussion about environmental as well as human health behavior and analytic techniques corresponding to sulphonamides.

Methods: Various results and discussion were extracted from technical journals and books published by different researchers from all over the world. The cited bibliographic references were intentionally investigated in order to extract relevant information related to the proposed work.

Results: In this review, the determination techniques such as UV-spectroscopy, Enthalpimetry, Immunosensor, Chromatography, Chemiluminescence, Photoinduced fluorometric determination and Capillary electrophoresis for sulphonamide determination were discussed in detail. Among them, High-performance liquid chromatography (HPLC) and UV-spectroscopy were effective and extensively used for screening sulphonamide.

Conclusion: Knowing the quantification and behavior of sulphonamide in aqueous solution is mandatory to opt for the suitable wastewater treatment required. Hence, choosing appropriate high precision and feasible screening techniques is necessary, which can be attained with this review.

背景：许多抗生素因其独特的特性而被广泛用作药物。其中，磺酰胺类是常用且主要用于细菌处理的方法，但是，难降解性使它们难以处理。因此，它们与环境和分析技术的相互作用需要全球范围内的相当大的关注。

目的：因此，本综述旨在提供有关磺胺类药物的环境以及人类健康行为和分析技术的详细讨论。

方法：从世界各地不同研究人员出版的技术期刊和书籍中提取各种结果和讨论。引用的书目参考文献经过有意调查，以提取与拟议工作相关的信息。

结果：在本综述中，详细讨论了测定紫外酰胺，紫外光谱，焓，免疫传感器，色谱，化学发光，光致荧光测定和毛细管电泳等测定技术。其中，高效液相色谱法（HPLC）和紫外光谱法是有效的，被广泛用于磺酰胺的筛选。

结论：了解水溶液中磺酰胺的定量和行为对于选择所需的合适废水处理是必不可少的。因此，选择适当的高精度和可行的筛选技术是必要的，通过本综述可以实现。