Background: Zeolitic imidazolate frameworks with three metals Zn, Co and Ag (ZIF-3M) and ZIF-67 were synthesized at room temperature and characterized with different techniques such as FESEM, BET, EDX and XRD. Then, the synthesized nanoparticles were successfully applied for the removal of levofloxacin from aqueous solutions.

Methods: To optimize the significant factors (i.e., pH, adsorbent dose and contact time), the response surface methodology (RSM) was implemented based on Box-Behnken design (BBD) in each step, an appropriate amount of adsorbent was added to 30 ppm of a solution containing levofloxacin and the pH was adjusted to the desired value with 0.1 M HCl or 0.1 M NaOH. The mixture was stirred at room temperature and then centrifuged at 7500 rpm for 3 min.

Results: The optimal conditions for each variable were performed using Box-Behnken design. Results revealed that ZIF-3M nanoparticles more efficiently remove levofloxacin than ZIF-67 in aqueous solution.

Conclusion: In this research, new three metals ZIF (ZIF-3M) nanoparticles were synthesized with Ag, Zn and Co in aqueous solution and characterized by different techniques. Results indicated successful synthesis with preserving ZIF framework. Results indicated that ZIF-3M has more ability for the removal of levofloxacin than ZIF-67. Isotherm studies showed that the most suitable model for the adsorption of levofloxacin onto ZIF-3M has a good agreement with the Langmuier model.

背景：在室温下合成具有锌，钴和银三种金属（ZIF-3M）和ZIF-67的沸石咪唑酸盐骨架，并使用FESEM，BET，EDX和XRD等不同技术进行表征。然后，合成的纳米颗粒被成功地用于从水溶液中去除左氧氟沙星。

方法：为了优化重要因素（例如，pH，吸附剂剂量和接触时间），在每个步骤中基于Box-Behnken设计（BBD）实施了响应面方法（RSM），将适量的吸附剂添加到30含左氧氟沙星的溶液的ppm，用0.1 M HCl或0.1 M NaOH将pH调节至所需值。将混合物在室温搅拌，然后以7500 rpm离心3分钟。

结果：使用Box-Behnken设计执行每个变量的最佳条件。结果显示，在水溶液中，ZIF-3M纳米颗粒比ZIF-67更有效地去除左氧氟沙星。

结论：本研究以Ag，Zn和Co为水溶液，分别合成了三种金属ZIF（ZIF-3M）纳米粒子，并采用不同的技术对其进行了表征。结果表明在保留ZIF框架的情况下成功合成。结果表明，ZIF-3M具有比ZIF-67更高的左氧氟沙星清除能力。等温线研究表明，最合适的左氧氟沙星吸附到ZIF-3M的模型与Langmuier模型有很好的一致性。