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The Synthesis and Use of BMS 204352 (MaxiPostTM)
Mini-Reviews in Organic Chemistry ( IF 2.3 ) Pub Date : 2020-01-31 , DOI: 10.2174/1570193x16666181228100254
Renato Dalpozzo 1
Affiliation  

MaxiPostTM is an interesting 3-fluorooxindole derivative, discovered in the late nineties of the last century as potassium channel opener. Since then, two different research fields were discovered: the discovery of new synthetic methods, especially asymmetric ones, and the in vitro and in vivo tests for its use as a drug for different diseases. This mini-review aims to summarize the state of art in both fields.



中文翻译:

BMS 204352(MaxiPost TM)的合成和使用

MaxiPostTM是一种有趣的3-氟代吲哚衍生物,在上世纪90年代后期作为钾通道开放剂被发现。从那时起,发现了两个不同的研究领域:发现了新的合成方法,尤其是不对称的合成方法,以及对其用作不同疾病药物的体外和体内试验。这份小型回顾旨在总结两个领域的最新技术。

更新日期:2020-01-31
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