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One-Pot Multicomponent Synthesis of Imidazole Rings in Acidic Ionic Liquids: A Review
Mini-Reviews in Organic Chemistry ( IF 2.3 ) Pub Date : 2020-11-30 , DOI: 10.2174/1570193x17666200226110645
Cosmas Chinweike Eze 1 , Mercy Amarachi Ezeokonkwo 2 , Benjamin Ebere Ezema 2 , Abraham Efeturi Onoabedje 2 , Fidelia Ngozika Ibeanu 1 , David Izuchukwu Ugwu 2 , Leonard Ebuka Onyeyilim 2 , James Anayochwkwu Ezugwu 2
Affiliation  

The design of the environmentally friendly approach to the synthesis of biologically important compounds without compromising the yield has been the focus of many chemists in recent years. The development of the one-pot synthesis of heterocycles in the presence of Ionic Liquids (ILs), used as both environmental media and catalysts, is efficient and environmentally sustainable. This review highlights the one-pot synthesis of imidazoles in acidic ILs in the past decade. Some reviews have been conducted on imidazoles, such as their pharmacological importance. Hence, we decided to focus on their synthesis in acidic ionic liquids, which the authors are not aware of any published literature.



中文翻译:

酸性离子液体中咪唑环的一锅多组分合成研究进展

近年来,在不影响收率的前提下设计合成生物学上重要的化合物的环保方法一直是许多化学家关注的焦点。在用作环境介质和催化剂的离子液体(ILs)存在下,一锅合成杂环的开发是有效且环境可持续的。这篇综述重点介绍了过去十年中酸性ILs中一锅法合成的咪唑。已经对咪唑进行了一些综述,例如其药理学重要性。因此,我们决定将重点放在酸性离子液体中的合成上,而作者们还没有任何公开的文献。

更新日期:2020-12-24
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