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PD-1 + T reg cells: a foe in cancer immunotherapy?
Nature Immunology ( IF 30.5 ) Pub Date : 2020-09-24 , DOI: 10.1038/s41590-020-0801-7
Halil-Ibrahim Aksoylar 1, 2 , Vassiliki A Boussiotis 1, 2
Affiliation  

The mechanisms that drive responses to PD-1-blocking immunotherapy in some but not all patients have been puzzling. A new study suggests that the balance of PD-1 expression levels between CD8+ T cells and Treg cells might provide an answer.

中文翻译:

PD-1 + T reg 细胞:癌症免疫疗法的敌人?

在一些但并非所有患者中驱动对 PD-1 阻断免疫疗法产生反应的机制一直令人费解。一项新的研究表明,CD8+ T 细胞和 Treg 细胞之间 PD-1 表达水平的平衡可能会提供答案。
更新日期:2020-09-24
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