There are many unknowns for pregnant women during the COVID-19 pandemic. Clinical experience of pregnancies complicated with infection by other coronaviruses e.g. SARS and MERS, has led to pregnant woman being considered potentially vulnerable to severe SARS-CoV-2 infection. Physiological changes during pregnancy have a significant impact on the immune system, respiratory system, cardiovascular function and coagulation. These may have positive or negative effects on COVID-19 disease progression. The impact of SARS-CoV-2 in pregnancy remains to be determined and a concerted, global effort is required to determine effects on implantation, fetal growth and development, labour and neonatal health. Asymptomatic infection presents a further challenge regarding service provision, prevention and management. As well as direct impacts of the disease, a plethora of indirect consequences of the pandemic will adversely affect maternal health including reduced access to reproductive health services, increased mental health strain and increased socioeconomic deprivation. In this review we explore the current knowledge of COVID-19 in pregnancy and signpost areas for further research to minimise its impact for women and their children.

中文翻译：

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怀孕和 COVID-19。

在 COVID-19 大流行期间，孕妇面临许多未知因素。妊娠并发其他冠状病毒（例如 SARS 和 MERS）感染的临床经验导致孕妇被认为可能容易受到严重 SARS-CoV-2 感染。怀孕期间的生理变化对免疫系统、呼吸系统、心血管功能和凝血功能有显着影响。这些可能对 COVID-19 疾病进展产生积极或消极影响。SARS-CoV-2 对妊娠的影响仍有待确定，需要全球共同努力来确定对着床、胎儿生长发育、分娩和新生儿健康的影响。无症状感染者对服务提供、预防和管理提出了进一步的挑战。除了该疾病的直接影响外，该流行病的大量间接后果还将对孕产妇健康产生不利影响，包括获得生殖健康服务的机会减少、心理健康压力增加以及社会经济贫困加剧。在这篇综述中，我们探讨了目前关于怀孕和路标领域的 COVID-19 知识，以进行进一步研究，以尽量减少其对妇女及其子女的影响。