In our work, one-step electro-deposition method was adopted to produce polyaniline (PANI) and functional multiwalled carbon nanotubes (f-MWCNTs) films on glass carbon electrodes, and the modified electrodes were applied as an electrochemical sensor for determination of 10-hydroxycamptothecine (10-HCPT). The f-MWCNTs were handled by ultrasound processing in concentrated oxidizing acid solution, which can obtain a wonderful dissolution in water and attach new functional groups, such as –COOH and –OH. Then, aniline monomer could polymerize on the surface easily. The surface characterization was investigated using various techniques including scanning electron microscope, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, and X-ray diffraction, and electro-catalytic properties were characterized by cyclic voltammetry and electrochemical impedance spectroscopy. Under optimal conditions, the resulting of PANI/f-MWCNTs sensor showed a wide linear range (3 × 10⁻⁹ to 7 × 10⁻⁷ mol L⁻¹) and a low detection limit (1 10⁻⁹ mol L⁻¹), which is attributing to its large special surface area and good conductivity. Moreover, the modified electrodes are convenient to fabricate, which can be used to detect 10-HCPT in urine samples successfully.

中文翻译：

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聚苯胺/f-MWCNTs的一步电沉积制备作为电化学传感器检测10-羟基喜树碱

在我们的工作中，采用一步电沉积法在玻璃碳电极上制备聚苯胺（PANI）和功能性多壁碳纳米管（f-MWCNTs）薄膜，并将改性电极用作电化学传感器，用于测定 10-羟基喜树碱（10-HCPT）。f-MWCNTs在浓氧化酸溶液中通过超声处理，可以很好地溶解在水中并附着新的官能团，如-COOH和-OH。然后，苯胺单体很容易在表面聚合。使用各种技术研究表面表征，包括扫描电子显微镜，傅里叶变换红外光谱，X射线光电子能谱和X射线衍射，通过循环伏安法和电化学阻抗谱表征了电催化性能。在最佳条件下，PANI/f-MWCNTs 传感器的结果显示出较宽的线性范围（3 × 10^-9至 7 × 10 ^-7 mol L ^-1）和低检测限（1 10 ^-9 mol L ^-1），这归因于其较大的比表面积和良好的导电性。此外，修饰电极制作方便，可成功检测尿样中的10-HCPT。