In this article, the preparation of porous polymeric scaffolds of the synthetic poly (isopropylideneglycerol methacrylate) (PIPGMA) is described combining two complementary techniques. Supercritical CO₂ (SCCO₂), has been used as foaming agent to obtain internal porosity by varying parameters such as pressure and depressurization time. However, the disadvantage of SCCO₂ technology is the formation of a non-porous skin layer described in the majority of the samples. This skin layer was modified by the breath figures technique (BF), providing superficial porosity to the polymeric sample. The result of using both techniques subsequently showed the formation of a porous network throughout the samples with inner and outer pores interconnected, characterized by scanning electron microscopy (SEM), micro X-ray computerized tomography scanning (micro CT), and processing those images with Image J. Finally, preliminary biological evaluation of the porous samples has been carried out in order to evaluate the biocompatibility and cellular viability of these scaffolds.

在本文中，描述了结合两种互补技术的合成聚甲基丙烯酸异亚丙基甘油酯（PIPGMA）多孔聚合物支架的制备。超临界CO ₂（SCCO ₂）已被用作发泡剂，以通过改变压力和减压时间等参数来获得内部孔隙率。但是，SCCO ₂的缺点技术是在大多数样品中描述了无孔皮肤层的形成。该表皮层通过呼吸图技术（BF）进行了改性，从而为聚合物样品提供了表面孔隙。随后使用这两种技术的结果表明，整个样品内部和外部孔相互连接形成了一个多孔网络，其特征在于扫描电子显微镜（SEM），微型X射线计算机断层扫描（micro CT）以及用图像J。最后，对多孔样品进行了初步的生物学评估，以评估这些支架的生物相容性和细胞生存力。