Prostaglandin signaling controls a wide range of biological processes from blood pressure homeostasis to inflammation and resolution thereof to the perception of pain to cell survival. Disruption of normal prostanoid signaling is implicated in numerous disease states. Prostaglandin signaling is facilitated by G-protein-coupled, prostanoid-specific receptors and the array of associated G-proteins. This review focuses on the expression, characterization, regulation, and mechanism of action of prostanoid receptors with particular emphasis on human isoforms.

中文翻译：

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前列腺素受体综述：表达，表征，调控和作用机制。

前列腺素信号传导控制着广泛的生物过程，从血压稳态到发炎，炎症的消退以及对疼痛到细胞存活的感知。正常前列腺素信号转导涉及许多疾病状态。G蛋白偶联的类前列腺素特异性受体和相关G蛋白的排列促进了前列腺素的信号传导。这篇综述着重于类前列腺素受体的表达，特征，调节和作用机理，特别着重于人类同工型。