The aim of this study was to explore the association between the building‐related occupants’ reported health symptoms and the indoor pollutant concentrations in a sample of 148 office rooms, within the framework of the European OFFICAIR research project. A large field campaign was performed in 37 office buildings among eight countries, which included (a) 5‐day air sampling of volatile organic compounds (VOCs), aldehydes, ozone, and NO₂ (b) collection of information from 1299 participants regarding their personal characteristics and health perception at workplace using online questionnaires. Stepwise and multilevel logistic regressions were applied to investigate associations between health symptoms and pollutant concentrations considering personal characteristics as confounders. Occupants of offices with higher pollutant concentrations were more likely to report health symptoms. Among the studied VOCs, xylenes were associated with general (such as headache and tiredness) and skin symptoms, ethylbenzene with eye irritation and respiratory symptoms, a‐pinene with respiratory and heart symptoms, d‐limonene with general symptoms, and styrene with skin symptoms. Among aldehydes, formaldehyde was associated with respiratory and general symptoms, acrolein with respiratory symptoms, propionaldehyde with respiratory, general, and heart symptoms, and hexanal with general SBS. Ozone was associated with almost all symptom groups.

中文翻译：

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欧洲写字楼主观健康症状与室内空气质量的关联：OFFICAIR 项目

本研究的目的是在欧洲 OFFICAIR 研究项目的框架内，在 148 个办公室房间的样本中，探索与建筑物相关的居住者报告的健康症状与室内污染物浓度之间的关联。在 8 个国家/地区的 37 座办公楼中进行了一次大型现场活动，其中包括 (a) 对挥发性有机化合物 (VOC)、醛类、臭氧和 NO ₂进行为期 5 天的空气采样(b) 使用在线问卷从 1299 名参与者那里收集关于他们在工作场所的个人特征和健康认知的信息。将个人特征作为混杂因素，应用逐步和多级逻辑回归来研究健康症状与污染物浓度之间的关联。污染物浓度较高的办公室的居住者更有可能报告健康症状。在研究的挥发性有机化合物中，二甲苯与全身（如头痛和疲倦）和皮肤症状有关，乙苯与眼睛刺激和呼吸道症状有关，a-蒎烯与呼吸道和心脏症状有关，d-柠檬烯与一般症状有关，苯乙烯与皮肤症状有关. 在醛类中，甲醛与呼吸道和全身症状有关，丙烯醛与呼吸道症状有关，丙醛具有呼吸道、全身和心脏症状，己醛具有一般 SBS。臭氧几乎与所有症状组有关。