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Krebs von den Lungen‐6 (KL‐6) is a pathophysiological biomarker of early‐stage acute hypersensitivity pneumonitis among pigeon fanciers
Clinical & Experimental Allergy ( IF 6.1 ) Pub Date : 2020-10-04 , DOI: 10.1111/cea.13744
Yuan Ji 1 , Stephen J Bourke 2 , Mark Spears 3 , Louise V Wain 4, 5 , Gavin Boyd 6 , Phillip P Lynch 7 , Matthew Cunningham 1 , Kenneth Boyd 8 , Iona Donnelly 1 , Nobuoki Kohno 9 , Charles McSharry 1
Affiliation  

Identifying early stages of hypersensitivity pneumonitis (HP) is hampered by variable presentation, heterogeneous or undetected causal antigens and lack of gold‐standard biomarkers. Krebs von den Lungen (KL)‐6 is pathophysiological biomarker of alveolar epithelial damage. Pigeon fanciers, susceptible to HP, provide a model to investigate early HP.

中文翻译:

Krebs von den Lungen-6 (KL-6) 是鸽友早期急性过敏性肺炎的病理生理生物标志物

识别过敏性肺炎 (HP) 的早期阶段受到多变的表现、异质性或未检测到的因果抗原以及缺乏金标准生物标志物的阻碍。Krebs von den Lungen (KL)-6 是肺泡上皮损伤的病理生理生物标志物。对 HP 敏感的鸽友提供了一个模型来研究早期 HP。
更新日期:2020-10-04
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