Don′t leave me this way! Iridium(III) phenanthroline anticancer complexes with different leaving groups (Z) could lead to lysosomal damage, catalysing the change of NADH/NAD⁺, decreasing the mitochondrial membrane potential (ΔΨ_m), increasing the level of reactive oxygen species (ROS), and eventually leading to apoptosis.

中文翻译：

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具有卤离子和吡啶离去基团的铱(III)菲咯啉配合物的制备和生物活性

不要这样离开我！具有不同离去基团（Z）的铱（III）菲咯啉抗癌复合物可导致溶酶体损伤，催化NADH / NAD ⁺的变化，降低线粒体膜电位（ΔΨ _m），增加活性氧（ROS）水平，并最终导致细胞凋亡。