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Grey matter abnormalities in first-episode mania: A systematic review and meta-analysis of voxel-based morphometry studies
Bipolar Disorders ( IF 5.4 ) Pub Date : 2020-09-22 , DOI: 10.1111/bdi.12995
Kamyar Keramatian 1 , Trisha Chakrabarty 1 , Gayatri Saraf 1 , Jairo V Pinto 1, 2 , Lakshmi N Yatham 1
Affiliation  

It has been proposed that different stages of bipolar disorder may be underpinned by distinct neurobiological substrates. However, structural neuroimaging studies in early stages of the illness are limited by small sample sizes yielding inconsistent findings. The purpose of this systematic review and meta-analysis, therefore, was to identify regional grey matter volume (GMV) changes that are consistently associated with first episode of mania (FEM).

中文翻译:

首发躁狂症中的灰质异常:基于体素的形态测量学研究的系统评价和荟萃分析

有人提出,双相情感障碍的不同阶段可能由不同的神经生物学基质支持。然而,疾病早期的结构神经影像学研究受到小样本量的限制,结果不一致。因此,本系统评价和荟萃分析的目的是确定与首次躁狂发作 (FEM) 始终相关的区域灰质体积 (GMV) 变化。
更新日期:2020-09-22
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