INTRODUCTION Epidemiology provides an avenue for identifying disease pathogenesis, hence determining national incidence, along with socioeconomic and demographic variables involved in iNPH, can provide direction in elucidating the etiology and addressing healthcare inequalities. METHODS To investigate incidence (per 100,000) of iNPH diagnoses applied to the inpatient population, with respect to sex, age, income, residence, and race/ethnicity, we queried the largest American administrative dataset (2008-2016), the National (Nationwide) Inpatient Sample (NIS), which surveys 20% of United States (US) discharges. RESULTS Annual national inpatient incidence (with 25th and 75th quartiles) for iNPH diagnoses was 2.86 (2.72, 2.93). Males had an inpatient incidence of 3.27 (3.11, 3.39), higher (p = 0.008) than female at 2.45 (2.41, 2.47). Amongst age groups inpatient incidence varied (p = 0.000004) and was largest amongst the 85+ group at 18.81 (16.40, 19.95). Individuals with middle/high income had an inpatient incidence of 2.96 (2.77, 3.06), higher (p = 0.008) than the 2.37 (2.24, 2.53) of low-income patients. Depending on whether patients lived in urban, suburban, or rural communities, inpatient incidence diverged (p = 0.01) as follows, respectively: 2.65; 2.66; 3.036. Amongst race/ethnicity (p = 0.000003), inpatient incidence for Whites, Blacks, Hispanics, Asian/Pacific Islanders, and Native Americans were as follows, respectively: 3.88 (3.69, 3.93), 1.065 (1.015, 1.14); 0.82 (0.76, 0.85); 0.43 (0.33, 0.52); 0.027 (0.026, 0.12). CONCLUSION In the US, inpatient incidence for iNPH diagnoses exhibited disparities between socioeconomic and demographic strata, emphasizing a healthcare inequality. Disproportionately, diagnoses were applied most to patients who were White, male, 65 and older, middle/high income, and living in rural communities.

中文翻译：

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美国特发性正常压力脑积水的住院诊断：人口统计学和社会经济差异

简介 流行病学提供了确定疾病发病机制的途径，因此确定全国发病率以及 iNPH 中涉及的社会经济和人口统计变量，可以为阐明病因和解决医疗保健不平等问题提供方向。方法 为了调查适用于住院人群的 iNPH 诊断的发生率（每 100,000 例），涉及性别、年龄、收入、居住地和种族/民族，我们查询了美国最大的行政数据集（2008-2016 年），全国（全国） ) 住院样本 (NIS)，它调查了美国 (US) 出院人数的 20%。结果 iNPH 诊断的全国年住院率（第 25 和第 75 个四分位数）为 2.86 (2.72, 2.93)。男性住院发生率为 3.27 (3.11, 3.39)，高于女性 (p = 0.008)，为 2.45 (2.41, 2.47)。不同年龄组的住院发病率各不相同（p = 0.000004），并且在 85+ 组中最高，为 18.81 (16.40, 19.95)。中等/高收入个体的住院发生率为 2.96 (2.77, 3.06)，高于 (p = 0.008) 低收入患者的住院发生率 2.37 (2.24, 2.53)。根据患者是居住在城市、郊区还是农村社区，住院发病率差异 (p = 0.01) 分别如下：2.65；2.66; 3.036。在种族/民族 (p = 0.000003) 中，白人、黑人、西班牙裔、亚洲/太平洋岛民和美洲原住民的住院发病率分别如下：3.88 (3.69, 3.93), 1.065 (1.015, 1.14)；0.82 (0.76, 0.85); 0.43 (0.33, 0.52); 0.027 (0.026, 0.12)。结论 在美国，iNPH 诊断的住院发病率表现出社会经济和人口阶层之间的差异，强调医疗保健不平等。不成比例地，诊断最适用于白人、男性、65 岁及以上、中/高收入和居住在农村社区的患者。