• The two functional groups (nitro and amino) were introduced into MIL-101(Fe) for tuning the atomically dispersed metal active sites.

• Benefiting from both geometric and electronic effects, the nitro-functionalized MIL-101(Fe) shows a superior electronic structure of active sites and low reaction energy barrier for the HO* formation.

• Nitro-functionalized MIL-101(Fe)-based biosensor was successfully employed to detect acetylcholinesterase activity and organophosphorus pesticide.

中文翻译：

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在有机金属框架中调整原子分散的铁位点可增强过氧化物酶样活性，从而实现灵敏的生物传感

• 将两个官能团（硝基和氨基）引入MIL-101（Fe）中，以调节原子分散的金属活性位。

• 得益于几何效应和电子效应，经过硝基官能化的MIL-101（Fe）对HO *的形成具有出色的活性位电子结构和低反应能垒。

• 基于硝基功能的MIL-101（Fe）基生物传感器已成功用于检测乙酰胆碱酯酶活性和有机磷农药。