Abstract

Despite the efforts of the global medical and scientific community, tuberculosis remains the leading cause of death from infectious diseases. The expectation of success associated with the development of new anti-TB drugs was not justified, and the attention of researchers was largely drawn to the creation of new mycobacterial strains for vaccination against tuberculosis. The proposed review contains current information on the existing vaccine strains and the development of new, genetically engineered strains for the prevention of tuberculosis and the prevention and treatment of other diseases. The review includes relevant information on the correlation between BCG vaccination and the frequency and severity of COVID-19 infection.

中文翻译：

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结核病疫苗：问题和前景（综述）

摘要

尽管全球医学和科学界做出了努力，结核病仍然是传染病死亡的主要原因。与开发新的抗结核药物相关的成功预期是不合理的，研究人员的注意力主要集中在创造新的结核病疫苗接种分枝杆菌菌株上。拟议的审查包含有关现有疫苗株的当前信息以及用于预防结核病和预防和治疗其他疾病的新的基因工程菌株的开发。该评价包括有关卡介苗疫苗接种与 COVID-19 感染频率和严重程度之间相关性的相关信息。