Abstract

On the example of published and new experimental data, it was shown that insulin-containing hydrogels based on copolymers of N-(2-D-glucose)acrylamide and acrylamide crosslinked by Concanavalin A can simulate one of the functions of the pancreas, i.e., they can secrete insulin upon an increase in the glucose concentration in the surrounding medium, including a two-stage mechanism with the maximum rate in the first stage.

中文翻译：

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用于控制胰岛素释放的聚合物水凝胶

摘要

在已发表的实验数据和新的实验数据示例中，研究表明，基于伴刀豆球蛋白A交联的N-（2-D-葡萄糖）丙烯酰胺和丙烯酰胺共聚物的含胰岛素水凝胶可以模拟胰腺的一种功能，即当周围介质中的葡萄糖浓度增加时，它们可以分泌胰岛素，包括两阶段机制，第一阶段的速率最高。