People living with HIV (PLWHIV) can reasonably expect near-normal longevity, yet many express a willingness to assume significant risks to be cured. We surveyed 200 PLWHIV who were stable on antiretroviral therapy (ART) to quantify associations between the benefits they anticipate from a cure and their risk tolerance for curative treatments. Sixty-five per cent expected their health to improve if cured of HIV, 41% predicted the virus would stop responding to medications over the next 20 years and 54% predicted experiencing serious medication side effects in the next 20 years. Respondents’ willingness to risk death for a cure varied widely (median 10%, 75th percentile 50%). In multivariate analyses, willingness to risk death was associated with expected long-term side effects of ART, greater financial resources and being employed (all P < 0.05) but was not associated with perceptions of how their health would improve if cured.

艾滋病毒携带者（PLWHIV）可以合理预期接近正常的寿命，但是许多人表示愿意承担重大的治愈风险。我们调查了200名接受抗逆转录病毒疗法（ART）稳定的PLWHIV，以量化他们预期从治疗中获得的收益与其对治疗的风险耐受性之间的关联。65％的人预期如果治愈HIV，他们的健康状况将得到改善，41％的人预测病毒将在未来20年内停止对药物的反应，而54％的人预测在未来20年内将出现严重的药物副作用。受访者愿意接受治疗而死亡的风险的意愿差异很大（中位数为10％，第75个百分位数为50％）。在多变量分析中，死亡风险的意愿与抗病毒治疗的预期长期副作用，更多的财务资源以及被雇用有关（所有P  <0.05），但与治愈后健康状况的看法无关。