The association of neutrophil-lymphocyte ratio (NLR) and CD34 expression level with PSA level, Gleason score, and clinical stage was investigated in patients with prostate cancer. The correlation between NLR and CD34 expression was also investigated to provide evidence supporting the use of NLR for predicting the prognosis of prostate cancer patients. Clinical data of 75 patients diagnosed with prostate cancer by prostate aspiration biopsy were retrospectively analyzed. The correlation between NLR, CD34 expression, and clinicopathological characteristics was analyzed using the χ2 test and one-way analysis of variance. The correlation between NLR and CD34 was determined using the Pearson coefficient. Disease free survival was estimated by Kaplan-Meier analysis. Both NLR and CD34 expression were significantly positively correlated with PSA, Gleason score, and clinical stage (P < 0.05 both). Patients in the NLRHigh/CD34High group were characterized by high PSA level and Gleason score and late clinical stage. NLR was positively correlated with CD34 expression (r = 0.529, P < 0.001). Pretreatment NLR was a valuable marker of prognosis in prostate cancer. NLR is positively correlated with CD34 expression.

中文翻译：

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前列腺癌外周血中性粒细胞-淋巴细胞比率与CD34表达之间的相关性。

研究了前列腺癌患者中性粒细胞-淋巴细胞比率（NLR）和CD34表达水平与PSA水平，格里森评分和临床分期的关系。还研究了NLR和CD34表达之间的相关性，以提供证据支持使用NLR预测前列腺癌患者的预后。回顾性分析75例经前列腺穿刺活检诊断为前列腺癌的患者的临床资料。使用χ2检验和单向方差分析分析NLR，CD34表达与临床病理特征之间的相关性。使用皮尔森系数确定NLR和CD34之间的相关性。通过Kaplan-Meier分析估计无病生存期。NLR和CD34表达均与PSA呈显着正相关，格里森评分和临床分期（均P <0.05）。NLRHigh / CD34High组的患者的特征在于PSA水平高，Gleason评分高以及临床晚期。NLR与CD34表达呈正相关（r = 0.529，P <0.001）。预处理NLR是前列腺癌预后的重要标志。NLR与CD34表达呈正相关。