The objective of root canal obturation is to achieve a fluid-tight seal. Recently, GuttaFlow bioseal (GB), a root canal sealer composed of polydimethylsiloxane, gutta-percha particles, and bioactive glass ceramics, has been developed, to enhance the sealing ability of root canal filling material. The objective of this study was to assess the sealing ability of GB using a subnanoliter-scaled fluid-flow measuring device and to compare with that of AH Plus (AH). The fluid flow in root canal-filled teeth using either gutta-percha cone (GP) with AH (GAR; n = 10) or GP with GB (GBR; n = 10) and in GP inserted in AH blocks (GA; n = 10) or GP inserted in GB blocks (GB; n = 10) was measured. In addition, fluid flow in sealer blocks of AH (A; n = 10) and GB (B; n = 10), which served as negative controls, was measured. Root canal-filled teeth using GP without any sealer (GR) acted as positive controls (n = 10). The leakage was obtained by calculating the volume of moved water by time (s), after stabilization of the fluid flow was achieved. Statistical analysis was performed using the Kruskal–Wallis test and Mann–Whitney U-test with Bonferroni correction. A value less than 0.00238 (0.05/21) was considered significantly different. The mean leakages (nL/s) in the groups are as follows: GAR, 0.0958 ± 0.0543; GBR, 0.0223 ± 0.0246; GA, 0.0644 ± 0.0803; GB, 0.0267 ± 0.0182; A, 0.0055 ± 0.0057; B, 0.0052 ± 0.005; and GR, 0.2892 ± 0.3018. The mean leakage in the GBR group was lower than that in the GAR group ( = 0.001), while the mean leakages in the GA and GB groups were not significantly different. GuttaFlow bioseal can be useful in single-cone obturation technique.

中文翻译：

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AH Plus和GuttaFlow Bioseal的密封能力

根管封闭的目的是实现液密密封。近来，已经开发了由聚二甲基硅氧烷，牙胶-胶颗粒和生物活性玻璃陶瓷组成的牙根管密封剂GuttaFlow bioseal（GB），以增强牙根管填充材料的密封能力。这项研究的目的是使用亚纳升规模的流体流量测量装置评估GB的密封能力，并与AH Plus（AH）进行比较。使用带有AH（GAR; n  = 10）的牙龈-锥（GP）或带有GB（GBR; n  = 10）的GP以及插入AH块的GP（GA; n  = 10）或插入GB块（GB; n  = 10）中的GP 。此外，AH密封块中的流体流动（A; 测定n  ＝ 10）和作为阴性对照的GB（B；n＝ 10）。使用不带任何密封剂（GR）的GP充填根管的牙齿作为阳性对照（n  = 10）。在达到流体流量稳定之后，通过计算随时间推移的移动水量来获得泄漏。使用Kruskal-Wallis检验和Mann-Whitney U检验以及Bonferroni校正进行统计分析。一种小于0.00238（0.05 / 21）的值被认为有显着差异。各组的平均泄漏量（nL / s）如下：GAR，0.0958±0.0543；GBR，0.0223±0.0246；GA，0.0644±0.0803；GB，0.0267±0.0182；A，0.0055±0.0057；B，0.0052±0.005；和GR，0.2892±0.3018。GBR组的平均渗漏低于GAR组（ = 0.001），而GA和GB组的平均渗漏没有显着差异。GuttaFlow生物密封可用于单锥孔封闭技术。