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methylclock: a Bioconductor package to estimate DNA methylation age.
Bioinformatics ( IF 5.8 ) Pub Date : 2020-09-22 , DOI: 10.1093/bioinformatics/btaa825
Dolors Pelegí-Sisó 1 , Paula de Prado 1 , Justiina Ronkainen 2 , Mariona Bustamante 1, 3 , Juan R González 1, 3
Affiliation  

Ageing is a biological and psychosocial process related to diseases and mortality. It correlates with changes in DNA methylation (DNAm) in all human tissues. Therefore, epigenetic markers can be used to estimate biological age using DNA methylation profiling across tissues.

中文翻译:

甲基时钟:用于估计 DNA 甲基化年龄的 Bioconductor 包。

衰老是一种与疾病和死亡率相关的生物学和心理社会过程。它与所有人体组织中 DNA 甲基化 (DNAm) 的变化相关。因此,表观遗传标记可用于通过跨组织的 DNA 甲基化分析来估计生物学年龄。
更新日期:2020-09-22
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