Heterogeneous catalytic aldol reaction has widely focused on tethering multiple functional groups upon support that can act together (for example, acid-base cooperation) to improve reaction rate beyond individual moiety alone. Here, a series of amine-functionalized fibers with additional surface wettability modification were prepared to promote aldol reaction in water. The result showed that an enhanced catalytic activity was achieved by introducing hydroxyl group to fiber. Hydrophilic prolinamide-functionalized fiber (PAN_EF-PLA) exhibited the best catalytic performance, and its activity proved to be higher than those of hydrophobic-modified fiber and even the small molecule prolinamide. This enhancement is attributed to that the favorable hydrophilic microenvironment consisting of hydroxyl group, residual cyano group and prolinamide facilitates the accessibility of reactants to catalytic sites and increases the rate of mass transfer in water for promoting reaction. This work provides an effective protocol to maximize performance of fiber-supported catalyst by appropriate wettability modification.

异构催化醛醇缩合反应已广泛地集中于在支持物上束缚多个官能团，这些官能团可共同起作用（例如酸碱协作），以提高反应速度，而不仅仅是单独的部分。在此，制备了一系列具有附加的表面润湿性改性的胺官能化纤维，以促进水中的羟醛反应。结果表明，通过在纤维中引入羟基可以提高催化活性。亲水性脯氨酰胺官能化纤维（PAN _EF-PLA）表现出最好的催化性能，并且其活性被证明比疏水改性纤维甚至小分子脯氨酰胺更高。这种增强归因于由羟基，残留的氰基和脯氨酰胺组成的有利的亲水微环境促进了反应物到达催化部位的可及性，并增加了水中的质量转移速率以促进反应。这项工作提供了一种有效的方案，可以通过适当的润湿性改性来最大化纤维负载催化剂的性能。