Bioactive ceramics, such as calcium phosphate and calcium sulfate, have gained attention with the increase of aged population. Contrast to bio-inert ceramics, such as alumina and zirconia, the strength of bioactive ceramics is much lower. The strength of calcium sulfate (CaSO₄) is the lowest among all. In the present study, two approaches, involving the refinement of microstructure and the addition of nano-particles, are combined to enhance the strength. Various powder-processing treatments are adopted to facilitate these approaches. A pre-grinding treatment is applied first to reduce the matrix CaSO₄ grain size. The nano-silica (SiO₂) particles are then fixed onto the CaSO₄ particles through an attrition milling process. The strength of CaSO₄ is enhanced by 60% by adding only 1 mass% nano-SiO₂ particles. The strength of the SiO₂-CaSO₄ composites follows the Orowan-Petch relationship, indicating that their strength is dominated by the flaws. The addition of nano-particles refines the matrix grain size, consequently, the flaw size.

随着老年人口的增加，诸如磷酸钙和硫酸钙等生物活性陶瓷受到关注。与生物惰性陶瓷（例如氧化铝和氧化锆）相比，生物活性陶瓷的强度要低得多。硫酸钙（CaSO ₄）的强度最低。在本研究中，结合了两种方法，包括微结构的细化和纳米颗粒的添加，以提高强度。采用各种粉末处理方法以促进这些方法。首先进行预研磨处理以减小基质CaSO _4的晶粒尺寸。然后将纳米二氧化硅（SiO ₂）颗粒固定在CaSO _4上研磨过程中产生的颗粒。通过仅添加1质量％的纳米SiO ₂颗粒，CaSO ₄的强度提高了60％。SiO ₂ -CaSO ₄复合材料的强度遵循Orowan-Petch关系，表明它们的强度主要由缺陷引起。纳米颗粒的添加改善了基体的晶粒尺寸，因此改善了缺陷尺寸。