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Antibacterial and fibrinolytic potential of Himalayan soft gold mushroom Cordyceps sinensis
Indian Journal of Biochemistry and Biophysics ( IF 1.476 ) Pub Date : 2020-09-21
Diva Gupta Agrawal, Sardul Singh Sandhu

The medicinal mushroom Cordyceps sinensis collected from Himalayan region of India was found to have bioactive compounds. The mycelia free culture filtrate obtained from fermentation of Cordyceps mycelia were partially purified by solvent-solvent extractions. The subsequent fractions were tested for their potential regarding antibacterial and fibrinolytic activity. The butanolic fraction and aqueous layer showed significant antibacterial activity against six bacterial strains.While the final aqueous layer and hexane fraction showed partial fibrin lytic capacity in comparison with commercially available streptokinase as a positive control. It was assumed that the metabolite fractions when purified further can act as good antibacterial and fibrinolytic agents.

中文翻译:

喜马拉雅软金菇冬虫夏草的抗菌和纤溶潜力

从印度喜马拉雅地区采集的药用冬虫夏草被发现具有生物活性化合物。虫草菌丝体发酵得到的无菌丝体培养滤液通过溶剂-溶剂萃取法部分纯化。测试随后的级分在抗菌和纤溶活性方面的潜力。丁醇级分和水层显示出对六种细菌菌株的显着抗菌活性。尽管最终的水层和己烷级分与作为阳性对照的商业链激酶相比具有部分血纤蛋白溶解能力。假定当进一步纯化时,代谢物级分可以充当良好的抗菌剂和纤溶剂。
更新日期:2020-09-21
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