Being an economical, simple, user-friendly on-field screening platform, microfluidic paper-based analytical devices ( μ PADs) have gained significant attention in the scientific community. Hitherto, μ PADs were fabricated by patterning hydrophobic regions using photoresist, wax crayons, solid-ink, plotting-machine, cutting paper via laser and conventional table-top solid wax printer. However, most of these methods needed sophisticated and proprietary instruments, with a complicated process required to forms a hydrophobic barrier, and result in low resolution. In the present work, to prepare a μ PAD using an inexpensive laminator to generate hydrophobic patterns of paraffin wax on cellulose paper has been demonstrated. Here, a predesigned mold coated with paraffin wax and a hot laminator to form an absolute hydrophobic wax pattern. The predesigned mold was created using a simple printing/copier paper followed by wax dip-ping. These fabricated μ PADs have be...

中文翻译：

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优化的蜡层压微流控纸基分析装置的实现

作为一种经济，简单，用户友好的现场筛选平台，微流体纸质分析设备（μPADs）在科学界引起了广泛关注。迄今为止，通过使用光刻胶，蜡笔，固体墨水，绘图机，激光切割纸和常规台式固体蜡打印机对疏水区域进行构图来制作μPAD。但是，这些方法大多数都需要复杂且专有的仪器，并且需要复杂的过程才能形成疏水性屏障并导致分离度低。在目前的工作中，已经证明了使用廉价的层压机制备μPAD以在纤维素纸上产生石蜡的疏水性图案。在这里，预先设计的模具涂有石蜡和热层压机以形成绝对的疏水蜡图案。使用简单的打印/复印纸，然后浸蜡，即可创建预先设计的模具。这些预制的μPAD已...