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Hyaluronidase-based swim-up for semen selection in patients with human papillomavirus semen infection
Biology of Reproduction ( IF 3.6 ) Pub Date : 2020-09-21 , DOI: 10.1093/biolre/ioaa173
Luca De Toni 1 , Ilaria Cosci 1 , Andrea Carosso 2 , Luisa Barzon 3 , Bruno Engl 4 , Carlo Foresta 1 , Andrea Garolla 1
Affiliation  

Infection by human papillomavirus (HPV) represents one of the most common sexually transmitted diseases in both men and women worldwide. Recently, the detection of HPV virions in the semen of a large percentage of sexually active men has been associated with detrimental effects on both sperm parameters and on assisted reproductive technologies (ART) treatment outcomes. Conventional semen washing procedure used in ART have proved to be ineffective in removing HPV bound to sperm, requiring the identification of more effective and specific methods.

中文翻译:

人乳头瘤病毒精液感染患者的基于透明质酸酶的精液选择

人乳头瘤病毒 (HPV) 感染是全世界男性和女性中最常见的性传播疾病之一。最近,在大部分性活跃男性的精液中检测到 HPV 病毒粒子与对精子参数和辅助生殖技术 (ART) 治疗结果的不利影响有关。ART 中使用的常规精液清洗程序已被证明无法去除与精子结合的 HPV,需要确定更有效和更具体的方法。
更新日期:2020-09-21
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