ABSTRACT

There are large inter-individual differences in slow wave sleep, which constitute a trait or phenotype. We investigated whether the manifestation of this trait is impacted by daytime sleeping after sleep deprivation, and to what extent it is robust to prior caffeine intake. N = 12 subjects underwent three 48 h periods of total sleep deprivation with different caffeine dosing regimens. There were significant, considerable, and robust inter-individual differences in slow wave sleep across nighttime sleep opportunities before, and daytime sleep after, total sleep deprivation, regardless of caffeine dosing. The robustness of this phenotype may have functional implications for individuals in around-the-clock operational settings.

摘要

慢波睡眠的个体差异很大，构成了一种性状或表型。我们调查了该特征的表现是否受到睡眠剥夺后白天睡眠的影响，以及在多大程度上对以前的咖啡因摄入有帮助。N = 12名受试者接受了三个48小时的全部睡眠剥夺，分别使用不同的咖啡因剂量方案。无论咖啡因剂量如何，在完全睡眠剥夺之前，夜间睡眠机会以及白天之后的白天睡眠机会之间，慢波睡眠之间存在显着，显着且强大的个体间差异。这种表型的鲁棒性可能会对全天候操作环境中的人员产生功能性影响。