Antibiotic use in animal production, including aquaculture, has become a controversial subject in recent years. It is unclear whether antibiotic use by fish hatcheries or farms is functionally related to the development of resistance in important human pathogens. Nevertheless, antimicrobial resistance is relevant to aquaculture because it may reduce the effectiveness of the limited treatment options available for fish health management. We used linear regression models to explore possible temporal trends in antibiotic susceptibility of several bacterial fish pathogens over a 20‐year period at 12 Idaho Department of Fish and Game (IDFG)‐operated hatcheries. Observed antibiotic susceptibility was variable among hatcheries and among pathogens. Predicted susceptibility was generally unchanged or increased on average over the study period, suggesting no significant loss in susceptibility to the antibiotics tested. Collectively, our results indicate that fish health management, including occasional antibiotic treatment, has not substantively influenced antibiotic susceptibility of pathogens at IDFG‐operated hatcheries.

中文翻译：

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二十年的磁盘扩散测试表明，爱达荷州鱼类和野味部门经营的孵化场分离出的多种病原体对抗生素的敏感性没有任何明显的损失

近年来，在包括水产养殖在内的动物生产中使用抗生素已成为有争议的主题。目前尚不清楚鱼孵化场或养殖场使用抗生素是否在功能上与重要人类病原体产生抗药性有关。然而，抗菌素耐药性与水产养殖有关，因为它可能会降低鱼类健康管理可用有限治疗方案的有效性。我们使用线性回归模型探索了爱达荷州鱼类与猎物部（IDFG）运营的孵化场在20年内对几种细菌性鱼类病原体的抗生素敏感性的可能时间趋势。在孵化场和病原体之间观察到的抗生素敏感性不同。在研究期间，预计的药敏性通常保持不变或平均增加，提示对测试抗生素的敏感性没有明显降低。总体而言，我们的结果表明，鱼类健康管理，包括偶尔的抗生素治疗，并未对IDFG经营的孵化场对病原体的抗生素敏感性产生实质性影响。