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Biomedical applications of Jones-matrix tomography to polycrystalline films of biological fluids
Journal of Innovative Optical Health Sciences ( IF 2.5 ) Pub Date : 2019-06-10 , DOI: 10.1142/s1793545819500172
V. A. Ushenko 1 , A. Yu. Sdobnov 2 , W. D. Mishalov 3 , A. V. Dubolazov 1, 4 , O. V. Olar 1 , V. T. Bachinskyi 5 , A. G. Ushenko 1 , Yu. A. Ushenko 1 , O. Ya. Wanchuliak 5 , I. Meglinski 2, 4, 6, 7, 8
Affiliation  

Algorithms for reconstruction of linear and circular birefringence-dichroism of optically thin anisotropic biological layers are presented. The technique of Jones-matrix tomography of polycrystalline films of biological fluids of various human organs has been developed and experimentally tested. The coordinate distributions of phase and amplitude anisotropy of bile films and synovial fluid taken from the knee joint are determined and statistically analyzed. Criteria (statistical moments of 3rd and 4th orders) of differential diagnostics of early stages of cholelithiasis and septic arthritis of the knee joint with excellent balanced accuracy were determined. Data on the diagnostic efficiency of the Jones-matrix tomography method for polycrystalline plasma (liver disease), urine (albuminuria) and cytological smears (cervical cancer) are presented.

中文翻译:

琼斯矩阵断层扫描在生物体液多晶薄膜中的生物医学应用

提出了用于重建光学薄各向异性生物层的线性和圆形双折射二色性的算法。各种人体器官的生物体液多晶膜的琼斯矩阵断层扫描技术已得到开发和实验测试。确定并统计分析取自膝关节的胆膜和滑液的相位和幅度各向异性坐标分布。确定了膝关节早期胆石症和脓毒性关节炎的鉴别诊断标准(3 阶和 4 阶统计矩),具有出色的平衡精度。介绍了琼斯矩阵断层扫描方法对多晶血浆(肝病)、尿液(白蛋白尿)和细胞学涂片(宫颈癌)的诊断效率数据。
更新日期:2019-06-10
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