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Development of myofibres and associated connective tissues in fish axial muscle: Recent insights and future perspectives
Differentiation ( IF 2.9 ) Pub Date : 2019-03-05 , DOI: 10.1016/j.diff.2019.02.007
Pierre-Yves Rescan

Fish axial muscle consists of a series of W-shaped muscle blocks, called myomeres, that are composed primarily of multinucleated contractile muscle cells (myofibres) gathered together by an intricate network of connective tissue that transmits forces generated by myofibre contraction to the axial skeleton. This review summarises current knowledge on the successive and overlapping myogenic waves contributing to axial musculature formation and growth in fish. Additionally, this review presents recent insights into muscle connective tissue development in fish, focusing on the early formation of collagenous myosepta separating adjacent myomeres and the late formation of intramuscular connective sheaths (i.e. endomysium and perimysium) that is completed only at the fry stage when connective fibroblasts expressing collagens arise inside myomeres. Finally, this review considers the possibility that somites produce not only myogenic, chondrogenic and myoseptal progenitor cells as previously reported, but also mesenchymal cells giving rise to muscle resident fibroblasts.



中文翻译:

鱼轴肌中肌纤维和相关结缔组织的发育:最新见解和未来展望

鱼的轴向肌由一系列W型肌块组成,称为肌醇,主要由多核收缩肌细胞(肌原纤维)组成,这些细胞由错综复杂的结缔组织网络聚集在一起,该组织将肌原纤维收缩产生的力传递到轴向骨骼。这篇综述总结了有关连续的和重叠的肌生波对鱼类轴向肌肉形成和生长的当前知识。此外,本综述提供了有关鱼类肌肉结缔组织发育的最新见解,重点是分离相邻的单体的早期胶原形成和肌肉结缔皮形成的后期(。只有在鱼苗阶段,当表达胶原蛋白的结缔成纤维细胞出现在Myomeres内时,才在鱼苗阶段完成。最后,该综述考虑了体节不仅产生如先前报道的肌原性,软骨原性和肌中隔祖细胞的可能性,而且还产生间充质细胞产生肌肉驻留成纤维细胞的可能性。

更新日期:2019-03-05
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