Abstract

Being characterized by reduced pleasure from social interaction, social anhedonia constitutes a transdiagnostic marker for various psychiatric disorders. However, the neural portrait of social anhedonia remains elusive because of heterogeneities of reward type and reward dynamics in previous studies. The present event-related potential study investigated neural dynamics in response to monetary and social rewards in social anhedonia. Event-related potential responses were examined when a high social anhedonia (HSA, N = 23) group and a low social anhedonia (LSA, N = 26) group were anticipating and consuming social and monetary rewards. LSA but not HSA participants showed an increased stimulus-preceding negativity (anticipatory phase) and and increased reward positivity (consummatory phase) for monetary as compared with social rewards. This group difference could spring from an increased relevance of social rewards or a general decline in affective responding due to a potential association between social anhedonia and depression. Our findings provide preliminary evidence for neural aberrations of the reward system in social anhedonia, which is contingent upon reward type and reward dynamics.

中文翻译：

---

社会性快感缺失中货币和社会奖励处理的神经动力学。

摘要

社交性快感缺乏症的特征是社交互动减少，构成了各种精神疾病的转诊标志。然而，由于先前研究中奖励类型和奖励动态的异质性，社交性快感缺乏症的神经画像仍然难以捉摸。目前与事件相关的潜在研究调查了社会性快感缺乏症中响应金钱和社会奖励的神经动力学。当社交性快感缺乏症（HSA，N  = 23）组和社交性快感缺乏症（LSA，N）较低时，检查与事件相关的潜在反应 = 26）小组正在预期并消耗社会和金钱奖励。LSA而非HSA参与者显示，与社会奖励相比，货币刺激之前的消极情绪（预期阶段）增加，货币的奖励积极性（消费阶段）增加。这种群体差异可能源于社交奖励的相关性增加或由于社交性快感缺乏症和抑郁症之间的潜在关联而导致的情感反应普遍下降。我们的发现为社交性快感缺乏症的奖励系统的神经畸变提供了初步证据，这取决于奖励类型和奖励动态。