Objective: Oscillometry is an alternative to continuous wave-Doppler (cw-Doppler) to determine peripheral artery disease (PAD) severity using the ankle-brachial-index (ABI). Cw-Doppler-ABI differentiates systolic pressure of ATP and ADP where either one of both values in most patients is higher (high) and the other value is lower (low). In contrast, oscillometric-ABI measures the strongest signal and hence misses the lower value. Both do not take pedal perfusion into consideration. Simultaneous determination of tissue microperfusion cares for pedal PAD. Methods: ABI was determined by cw-Doppler and oscillometry. Tissue-optical-perfusion-pressure (TOPP) was taken from the first toe using photoplethysmography. 323 patients were evaluated retrospectively in 3 independent groups. Group 1 (99 patients) compared TOPP and oscillometric-ABI with systolic cw-Doppler-pressure and cw-Doppler-ABI. In Group 2 (103 patients) TOPP was compared with toe pressure (TP). In Group 3 (121 symptomatic patients) TOPP and ABI at rest and after stress were compared (ultrasound examination and magnetic resonance angiography (MRA) or computer tomography angiography (CTA) as control).Results: Bland-Altman-plot analysis presented no significant difference between oscillometric-ABI and the high cw-Doppler-ABI (Group 1). TOPP showed a difference of 26mmHg to the low cw-Doppler-pressure and none to the high cw-Doppler-pressure. In Group 2 TOPP correlates to TP but presented a difference of 37mmHg. Group 3 showed weak or no correlation between ABI and walking distance. Oscillometric-ABI correlates significantly to TOPP. To conclude, data after stress present a better correlation than at rest.Conclusions: TOPP provides absolute values of pedal macro-/microcirculation at rest and after stress tests.

中文翻译：

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组织光学灌注压力（TOPP）：一种简化，更可靠，更快速的评估周围动脉疾病中踏板微循环的方法。

目的：示波法是连续波多普勒（cw-Doppler）的一种替代方法，可通过踝肱指数（ABI）确定周围动脉疾病（PAD）的严重程度。Cw-Doppler-ABI区分ATP和ADP的收缩压，在大多数患者中，这两个值之一较高（较高），而另一个较低（较低）。相反，示波法ABI测量最强的信号，因此错过了较低的值。两者都没有考虑踏板灌注。同时确定脚踏PAD的组织微灌流护理。方法：通过cw-Doppler和示波法测定ABI。使用光体积描记法从第一个脚趾获取组织光学灌注压（TOPP）。在3个独立组中回顾性评估了323例患者。第1组（99例患者）比较了TOPP和示波法-ABI与收缩期cw-多普勒压力和cw-多普勒-ABI。在第2组（103例患者）中，将TOPP与趾压（TP）进行了比较。在第3组（121例有症状的患者）中，比较了休息和压力后的TOPP和ABI（超声检查和磁共振血管造影（MRA）或计算机断层造影血管造影（CTA）作为对照）。结果：Bland-Altman图分析显示无显着性示波量表-ABI与高cw-多普勒-ABI之间的差异（第1组）。TOPP显示出与低cw-多普勒压力相差26mmHg，与高cw-多普勒压力相差无。在第2组中，TOPP与TP相关，但相差37mmHg。第3组显示ABI与步行距离之间无相关性或无相关性。示波法ABI与TOPP显着相关。最后，