Bifunctional squaramides as a branch of organo‐catalysts showed powerful strategies in the art of asymmetric synthesis, and they have been proved to be highly efficient and versatile catalysts for constructing complex molecular structures and chiral biologically active compounds. In this review, we summarized recent advances in bifunctional squaramide‐catalyzed asymmetric Mannich reactions.

中文翻译：

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方胺催化不对称曼尼希反应的最新进展

作为有机催化剂的一个分支的双功能方酰胺在不对称合成技术中显示了强大的策略，并且已被证明是用于构建复杂分子结构和手性生物活性化合物的高效和多功能催化剂。在这篇综述中，我们总结了双功能方酰胺催化的不对称曼尼希反应的最新进展。