Skin structure and function results from a dynamic interplay between dermal and epidermal cell types. Optimizing skin health through an effective and long‐lasting skin care regime therefore requires a global approach, encompassing various mechanisms to stimulate this interplay beyond the action scope of a classical topical solution. This study evaluates the impact of a novel home‐use device combining a topical serum, light‐emitting diodes and massage on the clinical signs of extrinsic skin aging. The innovative principle relies on potentiating the effect of active ingredients contained in the topical serum with visible and near infra‐red photons to prevent extracellular matrix degradation and promote its reconstruction. After in vitro and ex vivo investigations, a clinical study assessed the safety and efficacy of a daily treatment with the home‐use device for 28 days. A significant increases in skin density and radiance while reducing the wrinkles was obtained with no side effects.

中文翻译：

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新型家用设备用于光增强（LED）皮肤治疗的安全性和有效性。

皮肤结构和功能是真皮和表皮细胞类型之间动态相互作用的结果。因此，通过有效和持久的皮肤护理方案来优化皮肤健康需要一种全球方法，其中包括各种机制来激发这种相互作用，而这超出了经典局部解决方案的作用范围。这项研究评估了将局部血清，发光二极管和按摩相结合的新型家用设备对外在皮肤衰老临床症状的影响。创新原理依赖于用可见光和近红外光子增强局部血清中所含活性成分的作用，以防止细胞外基质降解并促进其重建。经过体外和离体调查后，一项临床研究评估了使用家用设备进行28天日常治疗的安全性和有效性。获得了皮肤密度和光泽的显着增加，同时减少了皱纹，而没有副作用。