A capillary atmospheric pressure photoionization (cAPPI) source was used to analyze polycyclic aromatic hydrocarbons (PAHs) in complex matrices like grilled meat extract and urban dust reference material, as well as screening for PAHs in aqueous samples such as tap and lake water. A high‐throughput workflow was developed that allowed rapid screening of unknown samples by direct solid‐phase microextraction (SPME) coupled with cAPPI‐MS, with confirmatory gas chromatography performed only for samples containing trace amounts of PAHs. Extraction times were as low as 15 s, with a total analysis time of 2 min per sample for screening. Limits of detections were in the low pg/ml range and in the subpg/ml range for the direct and chromatographic approach, respectively, with a linear dynamic range between two and three orders of magnitude, as determined for 15 model PAHs. This rapid approach represents an attractive way to screen samples containing nonpolar compounds using an ambient ionization source.

中文翻译：

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通过固相微萃取与毛细管大气压光电离质谱联用，对水和复杂样品基质中的PAHs进行快速筛选和定量。

毛细管大气压光电离（cAPPI）源用于分析复杂基质中的多环芳烃（PAHs），例如烤肉提取物和城市粉尘参考材料，以及筛查自来水和湖水等水性样品中的PAHs。开发了一种高通量工作流程，可通过直接固相微萃取（SPME）结合cAPPI-MS快速筛查未知样品，并仅对含有痕量PAHs的样品进行确证气相色谱分析。提取时间低至15 s，每个样品的总分析时间为2分钟。对于直接法和色谱法，检测限分别在低pg / ml范围内和在subpg / ml范围内，线性动态范围介于2个和3个数量级之间，根据15个模型PAH确定。这种快速方法代表了一种使用环境电离源筛选包含非极性化合物的样品的有吸引力的方法。