High‐frequency oscillations (HFOs) have shown promising utility in the spatial localization of the seizure onset zone for patients with focal refractory epilepsy. Comparatively few studies have addressed potential temporal variations in HFOs, or their role in the preictal period. Here, we introduce a novel evaluation of the instantaneous HFO rate through interictal and peri‐ictal epochs to assess their usefulness in identifying imminent seizure onset.

中文翻译：

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难治性癫痫中高频振荡率的发作前变异性

高频振荡 (HFO) 在局灶性难治性癫痫患者的癫痫发作区的空间定位中显示出有前景的效用。相对而言，很少有研究涉及 HFO 的潜在时间变化，或其在发作前期的作用。在这里，我们通过发作间期和围发作期引入了对瞬时 HFO 率的新评估，以评估它们在识别即将发作的癫痫发作方面的有用性。