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Use of the “FreeStyle Libre” glucose monitoring system in diabetic cats.
Research in Veterinary Science ( IF 2.4 ) Pub Date : 2020-09-18 , DOI: 10.1016/j.rvsc.2020.09.015
Verena Deiting , Reinhard Mischke

The aim of this study was to assess the “FreeStyle Libre” flash glucose monitoring system regarding its measurement accuracy and tolerability in cats. Results from 66 sensors applied to 34 predominantly diabetic cats are included. The behaviour during the attachment, wearing, and removal of the sensor and the skin site of attachment were assessed. Blood samples were regularly collected for comparative measurements (hexokinase method). Minimal signs of discomfort were noted, although the sensor was additionally fixed using individual skin stitches. Sensors, which stopped working in situ (70% (46/66)), had a median functional life of 8.3 (1.6–14) days. Skin reactions on the adhesive surface occurred after removal of 39% (23) of 59 sensors with assessable skin reaction (mild erythema: n = 21; superficial dermatitis: n = 2). Due to the upper limit of the measurement range of 27.8 mmol/l (500 mg/dl), the reading device displayed “Hi” in 62% (17/34) of cats repeatedly and/or for periods >1 h. Results were highly correlated with those of the reference method (rS = 0.90, n = 359). 67.7% (243/359) of the “FreeStyle libre” measurement values had a maximum deviation of 15% from reference measurements and 99.4% (357/359) were within the zones A and B of Parkes Consensus error grid analysis. In conclusion, the device proved to be practicable, less stressful for the animals and generated in general acceptable results. Although the upper limit of the measurement range is a limiting factor, the device promises to significantly facilitate the management of diabetic cats.



中文翻译:

在糖尿病猫中使用“ FreeStyle Libre”葡萄糖监测系统。

这项研究的目的是评估“ FreeStyle Libre”快速血糖监测系统在猫中的测量准确性和耐受性。包括来自66个传感器的结果,这些传感器应用于34只主要患有糖尿病的猫。评估了传感器在附着,佩戴和拆卸过程中的行为以及附着的皮肤部位。定期收集血样进行比较测量(己糖激酶法)。尽管使用单独的皮肤缝合线另外固定了传感器,但仍注意到了极少的不适迹象。停止原位工作的传感器(70%(46/66)),平均功能寿命为8.3(1.6-14)天。除去39个传感器中的39%(23)且可评估的皮肤反应(轻度红斑:n = 21;浅表皮炎:n = 2)后,发生粘着剂表面的皮肤反应。由于测量范围的上限为27.8 mmol / l(500 mg / dl),因此读取设备在62%(17/34)的猫中反复和/或在> 1 h的时间内显示“ Hi”。结果与参考方法的结果高度相关(rS  = 0.90,n  = 359)。“自由式自由”测量值中有67.7%(243/359)与参考测量值的最大偏差为15%,在“ Parkes共识”误差网格分析的A和B区中为99.4%(357/359)。总之,该设备被证明是可行的,对动物的压力较小,并且产生了总体可接受的结果。尽管测量范围的上限是一个限制因素,但该设备有望显着促进糖尿病猫的管理。

更新日期:2020-09-20
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