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High-Definition Transcranial Direct Current Stimulation Facilitates Emotional Face Processing in Individuals with High Autistic Traits: A Sham-Controlled Study.
Neuroscience Letters ( IF 2.5 ) Pub Date : 2020-09-19 , DOI: 10.1016/j.neulet.2020.135396
Yuxi Qiao 1 , Qian Hu 1 , Rongrong Xuan 1 , Qianhui Guo 1 , Yuqi Ge 2 , Han Chen 2 , Chunyan Zhu 1 , Gongjun Ji 1 , Fengqiong Yu 1 , Kai Wang 3 , Lei Zhang 1
Affiliation  

The deficit in emotional face processing is a critical impairment for individuals with high autistic traits. The temporalparietal junction(TPJ) is considered to be closely related to emotional face processing. The aim of this study was to examine the effect of highdefinition transcranial direct current stimulation (HD-tDCS) over the right temporal-parietal junction (rTPJ) on facial emotion processing of individuals with high autistic traits using eye-tracking technology. Twenty-nine participants with high autistic traits completed an eyetracking task (including happy, fearful and neutral faces) before and after five consecutive days of stimulation (anodal or sham). Results showed that anodal HD-tDCS significantly increased fixation time and fixation count in the mouth area, but this effect was not found after the sham stimulation. Moreover, this increased effect of mouth recognition with anodal rTPJ HD-tDCS was shown in both happy and fearful faces, but no remarkable difference was found in neutral faces. These findings suggest that right TPJ anodal HD-tDCS can facilitate emotional face processing in individuals with high autistic traits.



中文翻译:

高清晰度经颅直流电刺激可促进具有高自闭症特征的人的情绪面部处理:一项假对照研究。

情绪面孔处理的不足对于具有高自闭症特征的个人而言是严重的损害。颞顶结(TPJ)被认为与情感面孔处理密切相关。这项研究的目的是研究使用眼动追踪技术,对右颞颞顶交界处(rTPJ)进行高清经颅直流电刺激(HD-tDCS)对高自闭症患者面部情绪处理的影响。在连续五天(阳极或假手术)刺激前后,有29位具有高自闭症特征的参与者完成了眼球跟踪任务(包括快乐,恐惧和中性的面孔)。结果表明,阳极HD-tDCS显着增加了口腔区域的固定时间和固定次数,但在假刺激后未发现这种效果。此外,高兴和恐惧的面孔都显示出阳极rTPJ HD-tDCS增强了嘴部识别的效果,但在中性面孔上没有发现明显的差异。这些发现表明,正确的TPJ阳极HD-tDCS可以促进具有高自闭症特征的人的情绪面部处理。

更新日期:2020-09-24
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