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Vaccines for COVID-19: perspectives from nucleic acid vaccines to BCG as delivery vector system.
Microbes and Infection ( IF 5.8 ) Pub Date : 2020-09-19 , DOI: 10.1016/j.micinf.2020.09.004
Nina Marí G P de Queiroz 1 , Fabio V Marinho 1 , Marcelo A Chagas 1 , Luciana C C Leite 2 , E Jane Homan 3 , Mariana T Q de Magalhães 1 , Sergio C Oliveira 4
Affiliation  

This article discusses standard and new disruptive strategies in the race to develop an anti-COVID-19 vaccine. We also included new bioinformatic data from our group mapping immunodominant epitopes and structural analysis of the spike protein. Another innovative approach reviewed here is the use of BCG vaccine as priming strategy and/or delivery system expressing SARS-CoV-2 antigens.



中文翻译:

COVID-19疫苗:从核酸疫苗到BCG作为递送载体系统的观点。

本文讨论了开发抗COVID-19疫苗的竞赛中的标准和新型破坏性策略。我们还包括了来自我们小组的新的生物信息学数据,这些数据绘制了免疫优势表位和刺突蛋白的结构分析。本文讨论的另一种创新方法是使用BCG疫苗作为表达SARS-CoV-2抗原的引发策略和/或递送系统。

更新日期:2020-09-19
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