Cells of Mycobacterium alvei are known to contain a unique set of mycolic acids with a (ω-1)-methoxy group; although the various enzymes in the biosynthesis of other types of mycolic acid have been widely studied, the biosynthetic route to this substituent is unclear. We now define the stereochemistry of the (ω-1)-methoxy fragment as R, and describe the synthesis of a major R-(ω-1)-methoxy-mycolic acid and its sugar esters, and of two natural M. alvei diene mycolic acids.

中文翻译：

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肺分枝杆菌 (ω-1)-甲氧基分枝杆菌酸：绝对立体化学和合成。

已知肺分枝杆菌细胞含有一组独特的带有 (ω-1)-甲氧基的分枝杆菌酸；尽管已经广泛研究了其他类型霉菌酸生物合成中的各种酶，但该取代基的生物合成途径尚不清楚。我们现在将 (ω-1)-甲氧基片段的立体化学定义为R，并描述主要的R- (ω-1)-甲氧基分枝杆菌酸及其糖酯的合成，以及两种天然M. alvei二烯的合成霉菌酸。