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Effect of (co)polymers based on methacrylic acid on the state of cells of the immune system
Russian Chemical Bulletin ( IF 1.7 ) Pub Date : 2020-08-01 , DOI: 10.1007/s11172-020-2938-9
O. V. Zhukova , S. D. Zaitsev , S. A. Ryabov , E. V. Arkhipova , T. F. Kovaleva , I. V. Mukhina

A series of methacrylic acid co(polymers) were obtained using various reversible chain transfer agents. The molecular weight characteristics of the synthesized (co)polymers were determined using gel permeation chromatography. In vitro studies showed the absence of cytotoxicity of the obtained compounds against immune cells (peritoneal macrophages) and the absence of an effect on the functional activity of the cells.

中文翻译:

基于甲基丙烯酸的(共)聚合物对免疫系统细胞状态的影响

使用各种可逆链转移剂获得了一系列甲基丙烯酸共聚物。合成的(共)聚合物的分子量特征使用凝胶渗透色谱法测定。体外研究表明,所获得的化合物对免疫细胞(腹膜巨噬细胞)没有细胞毒性,并且对细胞的功能活性没有影响。
更新日期:2020-08-01
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