In this paper, we propose a novel design of channels for dilution of microfluidic samples having suspended particles without the use of a secondary buffer solution. The proposed design takes advantage of parallelization to augment the sample processing rate while maintaining a similar dilation performance. Seven different microchannel geometries are tested to identify the most efficient design. The dilation performance and service life have been substantially increased by using improvised design, in which microchannels are connected between headers, and a circular pillar array is provided at the inlet of the channel. Various parameters affecting the dilation performance are investigated, from which the critical parameters are found to be channel aspect ratio and flow Reynolds number. An empirical relation, which can estimate the output slurry concentration as a function of aspect ratio and flow Reynolds number, is proposed. Particle accumulation patterns inside the headers are reported, and factors affecting it are discussed. Further, a technique to increase microchannel service life is discussed.

在本文中，我们提出了一种新颖的通道设计，用于在不使用二级缓冲液的情况下稀释具有悬浮颗粒的微流体样品。提出的设计利用并行化的优势来提高样本处理速率，同时保持类似的扩展性能。测试了七个不同的微通道几何形状，以确定最有效的设计。通过使用改进的设计，其中微通道连接在集管之间，并且在通道的入口处提供了圆形的柱状阵列，大大提高了膨胀性能和使用寿命。研究了影响膨胀性能的各种参数，从中发现关键参数是通道长宽比和流雷诺数。经验关系 提出了可以估算出输出浆液浓度与长宽比和流雷诺数的函数的方法。报告了集管内部的颗粒堆积模式，并讨论了影响其的因素。此外，讨论了增加微通道使用寿命的技术。