Among several noninvasive evaluation methods of portal hypertension (PH), the measurement of spleen stiffness is a reliable method for predicting esophageal variceal bleeding; however, the underlying mechanisms for increased stiffness remain unclear. We attempted to elucidate the pathological changes to the spleen and the underlying mechanisms in patients with PH.

中文翻译：

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脾索中表达细胞红蛋白的细胞导致肝硬化患者的脾纤维化。

在门静脉高压症（PH）的几种无创评估方法中，脾硬度的测量是预测食管​​静脉曲张出血的可靠方法；然而，增加刚度的潜在机制仍不清楚。我们试图阐明 PH 患者脾脏的病理变化及其潜在机制。