To investigate the anterior segment in nanophthalmic eyes and their association with intraocular pressure after cataract surgery. Thirty-two nanophthalmic eyes (axial length [AL] < 18.5 mm) in 18 patients and 35 normal eyes (21 ≤ AL ≤ 24.5 mm) in 35 controls who had undergone uneventful cataract surgery were included. Swept-source optical coherence tomography was used to compare the anterior segment structures between the two groups. The associations between the anterior segment characteristics of nanophthalmic eyes and postoperative intraocular pressure (IOP) were also investigated. The IOP-lowering effect of cataract surgery was remarkably insufficient in nanophthalmic eyes. Peripheral anterior synechiae (PAS) were observed in 56% (18/32) of nanophthalmic eyes, and a characteristic boomerang-shaped iris was observed in 28% (9/32). The anterior surface of the iris seemed “smoother” in nanophthalmic eyes than in normal eyes. Schlemm’s canal (SC) diameter, SC area, trabecular meshwork (TM) thickness, TM width, and TM area were generally smaller in the nanophthalmic eyes. Younger age, higher preoperative IOP, broader PAS, and smaller SC area were main contributors to higher postoperative IOP. AL and SC diameter may also be of great importance in IOP prediction in patients without glaucoma surgery and PAS. The morphological features of the anterior segment in nanophthalmic eyes are significantly different from those of normal eyes. Influencing factors such as age, AL, preoperative IOP, extent of PAS, SC and TM size could all be prognostic for IOP after cataract surgery in nanophthalmic eyes. ClinicalTrails.gov, Trial registration number: NCT02182921 , Registered 8 July 2014.

中文翻译：

---

眼前节形态学特征：影响纳米眼白内障术后眼压的因素

探讨纳米眼眼前节及其与白内障术后眼压的关系。包括 18 名患者的 32 只纳米眼（轴长 [AL] < 18.5 mm）和 35 名接受白内障手术的对照组的 35 只正常眼（21 ≤ AL ≤ 24.5 mm）。扫描源光学相干断层扫描用于比较两组之间的眼前节结构。还研究了纳米眼的眼前节特征与术后眼压（IOP）之间的关联。在纳米眼中，白内障手术的降低眼压的效果明显不足。在 56% (18/32) 的纳米眼中观察到外周前粘连 (PAS)，在 28% (9/32) 中观察到特征性的回旋镖形虹膜。虹膜的前表面在纳米眼中看起来比在正常眼中“光滑”。纳米眼中的施累姆管 (SC) 直径、SC 面积、小梁网 (TM) 厚度、TM 宽度和 TM 面积通常较小。年龄较小、术前眼压较高、PAS 较宽和 SC 面积较小是术后眼压较高的主要原因。AL 和 SC 直径在未进行青光眼手术和 PAS 的患者的眼压预测中也可能非常重要。纳米眼眼前节的形态特征与正常眼有显着差异。年龄、AL、术前眼压、PAS范围、SC和TM大小等影响因素均可预测纳米眼白内障术后眼压。ClinicalTrails.gov，试验注册号：NCT02182921，2014 年 7 月 8 日注册。