Biobased 5‐(chloromethyl)furoate and 5‐methylfuroate esters can be deprotonated to function as furylogous lithium enolates, and the former can also undergo zinc insertion to access Reformatsky‐type chemistry. Carbon nucleophilicity represents hitherto little‐explored reactivity in these key carbohydrate‐derived platform molecules, expanding their synthetic utility and potentially opening up new sustainable product markets (e. g., in epoxy resins or biobased dyes).

中文翻译：

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通过基于5-（氯甲基）糠醛的碳亲核试剂实现可再生呋喃平台的多样化。

可以将生物基5-（氯甲基）糠酸酯和5-甲基糠酸酯脱质子化，以产生糠醛烯酸锂，前者还可以进行锌插入以进入Reformatsky型化学反应。碳亲核性代表了这些关键的碳水化合物衍生的平台分子迄今尚未探索的反应性，扩展了其合成用途，并有可能开拓新的可持续产品市场（例如，在环氧树脂或生物基染料中）。