Irrigation with treated wastewater (WW) has been promoted to meet global water demands. This study investigates the occurrence and accumulation of targeted phthalic acid esters (PAEs) and antibiotics in soil and Ipomoea aquatica Forssk. irrigated with WW discharged from six hybrid constructed wetlands (HCWs), with evaluation of the associated human health risks. Results revealed that HCWs can effectively reduce the transfer of PAEs and antibiotics to soil and I. aquatica. HCW2 (VF-SF-HF) was found to be most efficient for the removal of PAEs (68.4%-95.3%) and antibiotics (28.5%-99.4%). Among the targeted PAEs, the concentration of bis (2-ethyl) hexylphthalate (DEHP) was the highest in irrigation water, soil and I. aquatica, while benzylphthalate (BBP) exhibited the highest bioconcentration factor (BCF_F). Among the targeted antibiotics, the concentration of sulfapyridine (SPD) was highest in various environmental media, while norfloxacin (NFX) exhibited the highest BCF_F. The properties of PAEs and antibiotics were found to be responsible for the differential uptake patterns. The estimation of the threshold of toxicological concern and hazard quotient showed that I. aquatica irrigated with HCWs treated wastewater presented a minor risk to human health. However, comprehensive safety evaluation is required for the widespread use of HCWs treated wastewater for irrigation purposes.

促进了使用处理过的废水（WW）的灌溉，以满足全球对水的需求。这项研究调查了目标邻苯二甲酸酯（PAEs）和抗生素在土壤和Ipomoea aquatica Forssk中的发生和积累。用六个混合人工湿地（HCW）排放的WW进行灌溉，并评估相关的人类健康风险。结果表明，HCW可以有效减少PAE和抗生素向土壤和水生伊蚊的转移。HCW2（VF-SF-HF）被发现对去除PAE（68.4％-95.3％）和抗生素（28.5％-99.4％）最为有效。在目标PAE中，灌溉水，土壤和水生I. aquatica中邻苯二甲酸双（2-乙基）己酯（DEHP）的浓度最高。，而邻苯二甲酸苄酯（BBP）表现出最高的生物浓缩系数（BCF _F）。在目标抗生素中，磺胺吡啶（SPD）的浓度在各种环境介质中最高，而诺氟沙星（NFX）的BCF _F最高。发现PAE和抗生素的性质是差异摄取模式的原因。毒理学关注阈值和危害商数的估计表明，用医护人员处理过的废水灌溉的水生伊蚊对人类健康的危害较小。但是，需要将经过医护人员处理的废水广泛用于灌溉目的，进行全面的安全评估。