Theranostics is the integration of diagnosis and therapy, which significantly reduces side effects, and saves time and cost. During the past few years, nanoprobes (NPs) with aggregation-induced emission (AIE) have been developed for theranostic applications with excellent performance superior to the conventional type. In this review, we summarize the latest advancement of AIE NPs in theranostic applications. Especially, we focus on the design of multifunctional AIE molecules with both strong emission and high efficiency for the generation of reactive oxygen species and photothermal conversion, and the use of these agents to prepare NPs for more translational biomedical applications via image-guided phototherapy. Challenges, opportunities, and perspectives for the future of this field are also discussed at the end of this review.

中文翻译：

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具有聚集诱导发射的纳米探针，用于诊断学

Theranostics是诊断和治疗的集成，可显着减少副作用，并节省时间和成本。在过去的几年中，已开发出具有聚集诱导发射（AIE）的纳米探针（NPs），用于治疗诊断应用，其性能优于传统类型。在这篇综述中，我们总结了AIE NP在诊断学应用中的最新进展。特别是，我们专注于设计具有强发射性和高效率的多功能AIE分子，用于产生活性氧和进行光热转化，并利用这些试剂来制备NPs，以通过更多的翻译生物医学应用图像引导的光疗。在这篇评论的结尾还讨论了该领域的挑战，机遇和前景。