Abstract Introduction Antimicrobial resistance is a global health threat. It has been studied in humans and domestic animals, but there is a lack of data on wild animals. The objective of this study is the elucidation of its patterns in Staphylococcus spp. isolated from wild mammals of the Autonomous Community of Aragón (Spain). Material and Methods A total of 103 mammals (Artiodactyla, Carnivora, Chiroptera, Erinaceomorpha, and Lagomorpha) were studied. A recovery centre provided 32 and hunting 71. Nasal and faecal samples yielded 111 staphylococci, which were identified by matrix-assisted laser desorption/ionization–time of flight mass spectrometry. A susceptibility test to 11 antibiotics was carried out, and statistical analysis was performed. Results Some differences were detected in bacterial prevalence depending on how the mammal fed. Artiodactyla, mainly hunted, were predisposed to carry coagulase-positive staphylococci. The staphylococci species recovered were resistant to at least two classes of antibiotics, and were disseminated in all of the geographical areas studied. Conclusion Resistant staphylococci are widely distributed in the wild mammals in the areas of the study, but the resistance quantified in them is lower than that to be expected if the use of antibiotics in farms had a direct influence on the wildlife and its environment. On the other hand, resistance to antibiotics restricted to human use was widely disseminated in various wild animal species.

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葡萄球菌属 来自阿拉贡（西班牙）的野生哺乳动物：抗生素耐药性状况

摘要 引言 抗菌素耐药性是一个全球性的健康威胁。它已在人类和家畜中进行了研究，但缺乏野生动物的数据。本研究的目的是阐明其在葡萄球菌属中的模式。从阿拉贡（西班牙）自治社区的野生哺乳动物中分离。材料和方法 共研究了 103 种哺乳动物（偶蹄目、食肉目、翼翅目、刺猬亚目和兔形亚目）。一个回收中心提供了 32 个和 71 个狩猎。鼻腔和粪便样本产生了 111 个葡萄球菌，这些葡萄球菌通过基质辅助激光解吸/电离-飞行时间质谱法进行鉴定。对11种抗生素进行敏感性试验，并进行统计分析。结果 根据哺乳动物的喂养方式，检测到细菌流行率存在一些差异。偶蹄目，主要被猎杀，易携带凝固酶阳性葡萄球菌。回收的葡萄球菌对至少两类抗生素具有抗药性，并在所研究的所有地理区域传播。结论 耐药性葡萄球菌在研究区野生哺乳动物中广泛分布，但量化的耐药性低于农场使用抗生素对野生动物及其环境有直接影响的预期。另一方面，对仅限于人类使用的抗生素的耐药性在各种野生动物物种中广泛传播。并在所研究的所有地理区域传播。结论 耐药性葡萄球菌在研究区野生哺乳动物中广泛分布，但量化的耐药性低于农场使用抗生素对野生动物及其环境有直接影响的预期。另一方面，对仅限于人类使用的抗生素的耐药性在各种野生动物物种中广泛传播。并在所研究的所有地理区域传播。结论 耐药性葡萄球菌在研究区野生哺乳动物中广泛分布，但量化的耐药性低于农场使用抗生素对野生动物及其环境有直接影响的预期。另一方面，对仅限于人类使用的抗生素的耐药性在各种野生动物物种中广泛传播。