当前位置: X-MOL 学术Int. J. Paleopathol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
A very rare case of possible actinomycosis of the mandible from the Middle Ages.
International Journal of Paleopathology ( IF 1.2 ) Pub Date : 2020-09-16 , DOI: 10.1016/j.ijpp.2020.09.001
Lenka Vargová 1 , Ladislava Horáčková 2 , Kateřina Vymazalová 1 , Alena Němečková 3 , Zdeněk Tvrdý 4 , Luděk Galuška 5 , Jiří Mitáček 6 , Dana Fialová 7
Affiliation  

Objective

Documented cases of actinomycosis in archaeological skeletons are very rare, especially from Central Europe. Our contribution will help facilitate the differential diagnosis of this disease for other paleopathologists.

Material

This paper describes a pathological finding of the skeleton of a 40-year-old male from a burial ground in Sady-Špitálky (Czech Republic) dated to the 10th-12th century.

Methods

The affected skeleton was evaluated as a probable case of actinomycosis on the basis of a detailed macroscopic, X-ray and histological examination. The osteolytic foci examined were compared with similar changes caused by tuberculosis, syphilis and mycoses.

Results

The character and location of the defect on the mandible is indicative of organ actinomycosis and is also reflected by the lytic lesion observed on a lumbar vertebra.

Conclusions

The described case can be considered one of the very rare paleopathological findings of possible actinomycosis in humans in Central Europe.

Significance

Good evidence of bone actinomycosis findings may be beneficial for further paleopathological and epidemiological studies, especially for research focused on the diachronic development of actinomycosis in Europe. In doing so, all available factors, such as hygiene habits, nutrition, social structure and overall health of the population that could be causally related to its origin, course and treatment, can be taken into account.

Limitations

The mandible of the studied individual was damaged, especially in the area affected by the lesion, so the paleopathological analysis was difficult to perform.

Suggestion for the future research

In future, actinomycosis in this skeleton may be confirmed by bio-molecular analysis.



中文翻译:

一个非常罕见的可能是中世纪下颌骨放线菌病的病例。

客观的

考古骨骼中记录的放线菌病病例非常罕见,尤其是来自中欧。我们的贡献将有助于促进其他古病理学家对这种疾病的鉴别诊断。

材料

本文描述了对 10 至 12 世纪 Sady-Špitálky(捷克共和国)墓地的一具 40 岁男性骨骼的病理发现。

方法

根据详细的宏观、X 射线和组织学检查,受影响的骨骼被评估为放线菌病的可能病例。将检查的溶骨病灶与结核病、梅毒和真菌病引起的类似变化进行比较。

结果

下颌骨缺损的特征和位置表明存在器官放线菌病,也反映在腰椎上观察到的溶解性病变。

结论

所描述的病例可以被认为是中欧人类可能发生放线菌病的非常罕见的古病理学发现之一。

意义

骨放线菌病发现的良好证据可能有利于进一步的古病理学和流行病学研究,特别是对欧洲放线菌病历时发展的研究。在这样做时,可以考虑所有可用因素,例如可能与其起源、病程和治疗有因果关系的人口的卫生习惯、营养、社会结构和整体健康。

限制

被研究个体的下颌骨受损,特别是受病变影响的区域,因此难以进行古病理学分析。

对未来研究的建议

未来,该骨骼中的放线菌病可能会通过生物分子分析得到证实。

更新日期:2020-09-16
down
wechat
bug